Frequency of various types of leukaemias diagnosed at PAF hospital mianwali

To determine the frequencies of various types of leukaemias in a secondary care hospital. Descriptive. PAF Hospital Mianwali, from Jan 2009 to Dec 2012. Record of all the cases of acute lymphoblastic leukaemia [ALL], acute myeloid leukaemia [AML], chronic lymphocytic leukaemia [CLL] and chronic myeloid leukaemia [CML] diagnosed during the period of study was retrieved from the laboratory and total number of leukaemia cases were counted. The ages and the genders of the patients were noted. Median age at diagnosis for each type of leukaemia was worked out. Frequency of each leukaemia type was noted and relative frequency was calculated as percentage. Out of a total of 67 patients, AML was diagnosed in 22 [32.8%], CML in 16 [23.8%], ALL in 15 [22.4%] and CLL in 14 [20.9%] cases. Median age at diagnosis for ALL, AML, CLL and CML was 5,41, 70 and 40 years respectively while male to female ratio was 2.7,1.4,1.3 and 1.5 respectively. AML was the commonest leukaemia type, followed by CML, ALL and CLL. In children, ALL was found to be four times more common than AML

Surge of malaria in Mianwali due to floods: perspective from a secondary care hospital

Objective: To assess the magnitude of flood related rise in the frequency of malaria, diagnosed at a secondary care hospital, during 2007-2011

Study Design: Cross sectional descriptive study

Place and Duration of Study: Pakistan Air Force hospital Mianwali, from 1[st] Jan 2007 to 31[st] Dec 2011

Patients and Methods: Monthly records of hospital laboratory patients with peripheral blood smears, positive for malarial parasites, were counted from 1[st] Jan 2007 to 31[st] Dec 2011. Frequencies of vivax and falciparum malarial cases diagnosed each year during 2007-2009 were compared with the corresponding frequencies during the year of floods i.e. 2010, and the following year i.e. 2011

Results: When compared with the mean of the annual frequencies during 2007-2009, there was a rise in the total number of malaria cases by 1.3 times in 2010; while next year, i.e. during 2011, the rise was 3.0 times. During the period 2007-2011, vivax malaria cases always peaked during the months of September each year while falciparum malaria cases had a spike in the months of November

Conclusion: Massive floods resulted in a rise in the frequency of malaria cases during flood season and as an after math during the next malarial season. Planning for prevention and control should be done accordingly. Spread of falciparum malaria following the floods demands more efforts towards halting its possible rise in Mianwali district

Ocular features, clinical profile and results of surgical intervention in a series of patients with Port Wine Stain and neurofibromatosis

To describe the ocular features, clinical profile and results of surgical intervention in a series of patients with facial port-wine stain [PWS] and neurofibromatosis [NF] in the pediatric age group. All consecutive patients having PWS and NF presenting between January 2011 and April 2012 were included. Their systemic and ocular features were recorded. Imaging study of brain and orbits was carried out where required. Appropriate surgical interventions were carried out as indicated. These included trabeculectomy, cycloablation, excision of episcleral haemangioma and vitreo-retinal surgery. Patients were followed up for complications and control of intra ocular pressure [IOP]. A total of 9 eyes of 8 patients were included. At presentation IOP in the involved eye ranged from 6 to 42 mmHg [mean 25.00 +/- 12.23]. Glaucoma was present in 6 eyes. Episcleral haemangioma was noticed in one patient, retinal detachment [RD] was seen in 2 patients. Diffuse choroidal thickening on B scan was noted in 5 eyes of patients with PWS. After applying the appropriate management option, IOP on last follow up ranged from 6 to 24mmHg [mean 13.44 +/- 5.43] in the involved eye the last follow up ranged from 6 to 24mmHg [mean 13.44 +/- 5.43] in the involved eye. The difference between IOP of the involved eyes at initial presentation and that recorded at the last follow-up was significant [p=0.005]. Patients with SWS and NF present with varied clinico-ocular profiles and therapeutic interventions are individualized according to the ocular involvement. Post operative complications after treatment of glaucoma in such patients can largely be prevented with special measures taken per-operatively

Toxic optic neuropathy and bilateral symmetrical putamen infarcts

The presented case describes the correlation of ocular findings with those of neuroimaging in a patient having a history of methanol ingestion prior to development of painless loss of vision